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J. Funct. Biomater. 2012, 3(2), 239-256; doi:10.3390/jfb3020239

Stimuli-Responsive Polymer Brushes for Flow Control through Nanopores

1,*  and 2
1 Kodak Research Laboratories, Eastman Kodak Company, Rochester, NY 14620, USA 2 Department of Materials Science and Engineering, North Carolina State University, Raleigh, NC 27695, USA
* Author to whom correspondence should be addressed.
Received: 31 December 2011 / Revised: 16 March 2012 / Accepted: 19 March 2012 / Published: 26 March 2012
(This article belongs to the Special Issue Stimuli Responsive Biomaterials)
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Responsive polymers attached to the inside of nano/micro-pores have attracted great interest owing to the prospect of designing flow-control devices and signal responsive delivery systems. An intriguing possibility involves functionalizing nanoporous materials with smart polymers to modulate biomolecular transport in response to pH, temperature, ionic concentration, light or electric field. These efforts open up avenues to develop smart medical devices that respond to specific physiological conditions. In this work, an overview of nanoporous materials functionalized with responsive polymers is given. Various examples of pH, temperature and solvent responsive polymers are discussed. A theoretical treatment that accounts for polymer conformational change in response to a stimulus and the associated flow-control effect is presented.
Keywords: smart membranes; signal responsive polymers; polymer brushes; computational modeling; flow control; nanofluidic valve; simulation smart membranes; signal responsive polymers; polymer brushes; computational modeling; flow control; nanofluidic valve; simulation
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Adiga, S.P.; Brenner, D.W. Stimuli-Responsive Polymer Brushes for Flow Control through Nanopores. J. Funct. Biomater. 2012, 3, 239-256.

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