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Stimuli-Responsive Polymer Brushes for Flow Control through Nanopores
Kodak Research Laboratories, Eastman Kodak Company, Rochester, NY 14620, USA
Department of Materials Science and Engineering, North Carolina State University, Raleigh, NC 27695, USA
* Author to whom correspondence should be addressed.
Received: 31 December 2011; in revised form: 16 March 2012 / Accepted: 19 March 2012 / Published: 26 March 2012
Abstract: Responsive polymers attached to the inside of nano/micro-pores have attracted great interest owing to the prospect of designing flow-control devices and signal responsive delivery systems. An intriguing possibility involves functionalizing nanoporous materials with smart polymers to modulate biomolecular transport in response to pH, temperature, ionic concentration, light or electric field. These efforts open up avenues to develop smart medical devices that respond to specific physiological conditions. In this work, an overview of nanoporous materials functionalized with responsive polymers is given. Various examples of pH, temperature and solvent responsive polymers are discussed. A theoretical treatment that accounts for polymer conformational change in response to a stimulus and the associated flow-control effect is presented.
Keywords: smart membranes; signal responsive polymers; polymer brushes; computational modeling; flow control; nanofluidic valve; simulation
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Adiga, S.P.; Brenner, D.W. Stimuli-Responsive Polymer Brushes for Flow Control through Nanopores. J. Funct. Biomater. 2012, 3, 239-256.
Adiga SP, Brenner DW. Stimuli-Responsive Polymer Brushes for Flow Control through Nanopores. Journal of Functional Biomaterials. 2012; 3(2):239-256.
Adiga, Shashishekar P.; Brenner, Donald W. 2012. "Stimuli-Responsive Polymer Brushes for Flow Control through Nanopores." J. Funct. Biomater. 3, no. 2: 239-256.