Moonlighting with WDR5: A Cellular Multitasker
AbstractWDR5 is a highly conserved WD40 repeat-containing protein that is essential for proper regulation of multiple cellular processes. WDR5 is best characterized as a core scaffolding component of histone methyltransferase complexes, but emerging evidence demonstrates that it does much more, ranging from expanded functions in the nucleus through to controlling the integrity of cell division. The purpose of this review is to describe the current molecular understandings of WDR5, discuss how it participates in diverse cellular processes, and highlight drug discovery efforts around WDR5 that may form the basis of new anti-cancer therapies. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Guarnaccia, A.D.; Tansey, W.P. Moonlighting with WDR5: A Cellular Multitasker. J. Clin. Med. 2018, 7, 21.
Guarnaccia AD, Tansey WP. Moonlighting with WDR5: A Cellular Multitasker. Journal of Clinical Medicine. 2018; 7(2):21.Chicago/Turabian Style
Guarnaccia, Alissa D.; Tansey, William P. 2018. "Moonlighting with WDR5: A Cellular Multitasker." J. Clin. Med. 7, no. 2: 21.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.