Decoding the Secret of Cancer by Means of Extracellular Vesicles
AbstractOne of the recent outstanding developments in cancer biology is the emergence of extracellular vesicles (EVs). EVs, which are small membrane vesicles that contain proteins, mRNAs, long non-coding RNAs, and microRNAs (miRNAs), are secreted by a variety of cells and have been revealed to play an important role in intercellular communications. These molecules function in the recipient cells; this has brought new insight into cell-cell communication. Recent reports have shown that EVs contribute to cancer cell development, including tumor initiation, angiogenesis, immune surveillance, drug resistance, invasion, metastasis, maintenance of cancer stem cells, and EMT phenotype. In this review, I will summarize recent studies on EV-mediated miRNA transfer in cancer biology. Furthermore, I will also highlight the possibility of novel diagnostics and therapy using miRNAs in EVs against cancer. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Kosaka, N. Decoding the Secret of Cancer by Means of Extracellular Vesicles. J. Clin. Med. 2016, 5, 22.
Kosaka N. Decoding the Secret of Cancer by Means of Extracellular Vesicles. Journal of Clinical Medicine. 2016; 5(2):22.Chicago/Turabian Style
Kosaka, Nobuyoshi. 2016. "Decoding the Secret of Cancer by Means of Extracellular Vesicles." J. Clin. Med. 5, no. 2: 22.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.