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J. Clin. Med. 2015, 4(2), 343-359; doi:10.3390/jcm4020343

Age-Related Macular Degeneration: Advances in Management and Diagnosis

Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
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Author to whom correspondence should be addressed.
Academic Editors: Lindsay Farrer and Margaret DeAngelis
Received: 24 December 2014 / Revised: 24 December 2014 / Accepted: 20 January 2015 / Published: 12 February 2015
(This article belongs to the Special Issue Age-Related Macular Disease)
View Full-Text   |   Download PDF [293 KB, uploaded 12 February 2015]   |  

Abstract

Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in older populations in industrialized nations. AMD is a late-onset deterioration of photoreceptors and retinal pigment epithelium in the central retina caused by various environmental and genetic factors. Great strides in our understanding of AMD pathogenesis have been made in the past several decades, which have translated into revolutionary therapeutic agents in recent years. In this review, we describe the clinical and pathologic features of AMD and present an overview of current diagnosis and treatment strategies. View Full-Text
Keywords: age-related macular degeneration; choroidal neovascularization; fundus autofluorescence; fluorescein angiography; optical coherence tomography; retina; vascular endothelial growth factor; visual impairment age-related macular degeneration; choroidal neovascularization; fundus autofluorescence; fluorescein angiography; optical coherence tomography; retina; vascular endothelial growth factor; visual impairment
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Yonekawa, Y.; Miller, J.W.; Kim, I.K. Age-Related Macular Degeneration: Advances in Management and Diagnosis. J. Clin. Med. 2015, 4, 343-359.

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