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An Update on Translating Stem Cell Therapy for Stroke from Bench to Bedside
AbstractWith a constellation of stem cell sources available, researchers hope to utilize their potential for cellular repair as a therapeutic target for disease. However, many lab-to-clinic translational considerations must be given in determining their efficacy, variables such as the host response, effects on native tissue, and potential for generating tumors. This review will discuss the current knowledge of stem cell research in neurological disease, mainly stroke, with a focus on the benefits, limitations, and clinical potential.
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Dailey, T.; Metcalf, C.; Mosley, Y.I.; Sullivan, R.; Shinozuka, K.; Tajiri, N.; Pabon, M.; Acosta, S.; Kaneko, Y.; Loveren, H.V.; Borlongan, C.V. An Update on Translating Stem Cell Therapy for Stroke from Bench to Bedside. J. Clin. Med. 2013, 2, 220-241.View more citation formats
Dailey T, Metcalf C, Mosley YI, Sullivan R, Shinozuka K, Tajiri N, Pabon M, Acosta S, Kaneko Y, Loveren HV, Borlongan CV. An Update on Translating Stem Cell Therapy for Stroke from Bench to Bedside. Journal of Clinical Medicine. 2013; 2(4):220-241.Chicago/Turabian Style
Dailey, Travis; Metcalf, Christopher; Mosley, Yusef I.; Sullivan, Robert; Shinozuka, Kazutaka; Tajiri, Naoki; Pabon, Mibel; Acosta, Sandra; Kaneko, Yuji; Loveren, Harry V.; Borlongan, Cesar V. 2013. "An Update on Translating Stem Cell Therapy for Stroke from Bench to Bedside." J. Clin. Med. 2, no. 4: 220-241.