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J. Clin. Med. 2013, 2(4), 188-200; doi:10.3390/jcm2040188
Article

Can Zoledronic Acid be Beneficial for Promoting Tumor Response in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy?

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Received: 16 August 2013; in revised form: 5 September 2013 / Accepted: 11 September 2013 / Published: 16 October 2013
(This article belongs to the Special Issue Prevention and Treatment of Bone Metastases from Breast Cancer)
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Abstract: The antitumor effect of bisphosphonates (BPs) is under increasing scrutiny. Preclinical and clinical evidence has shown that BPs might sensitize breast tumors to chemotherapy. Here, we present a review of current preclinical and clinical evidence for antitumor effects of BPs, and evaluate how BPs might play a role in neoadjuvant treatment of women with breast cancer.
Keywords: bisphosphonates; zoledronic acid; chemotherapy; neoadjuvant; postmenopausal bisphosphonates; zoledronic acid; chemotherapy; neoadjuvant; postmenopausal
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Charehbili, A.; Fontein, D.B.Y.; Kroep, J.R.; Liefers, G.-J.; Nortier, J.W.R.; Velde, C.J.H. Can Zoledronic Acid be Beneficial for Promoting Tumor Response in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy? J. Clin. Med. 2013, 2, 188-200.

AMA Style

Charehbili A, Fontein DBY, Kroep JR, Liefers G-J, Nortier JWR, Velde CJH. Can Zoledronic Acid be Beneficial for Promoting Tumor Response in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy? Journal of Clinical Medicine. 2013; 2(4):188-200.

Chicago/Turabian Style

Charehbili, Ayoub; Fontein, Duveken B.Y.; Kroep, Judith R.; Liefers, Gerrit-Jan; Nortier, Johannes W.R.; Velde, Cornelis J.H. 2013. "Can Zoledronic Acid be Beneficial for Promoting Tumor Response in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy?" J. Clin. Med. 2, no. 4: 188-200.

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