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Vaccines 2017, 5(2), 14; doi:10.3390/vaccines5020014

Disease Prevention: An Opportunity to Expand Edible Plant-Based Vaccines?

1
Departamento de Biología Marina, Universidad Católica del Norte, Programa de Doctorado en Biología y Ecología Aplicada, Coquimbo 1780000, Chile
2
Departamento de Ingeniería en Alimentos, Universidad de La Serena, Programa de Doctorado en Ingeniería en Alimentos y Bioprocesos, La Serena 1700000, Chile
3
Departamento de Biología, Universidad de La Serena, Programa de Doctorado en Ingeniería en Alimentos y Bioprocesos, La Serena 1700000, Chile
4
Facultad de Salud, Universidad Autónoma de Chile, Talca 3460000, Chile
5
Departamento de Química, Universidad de La Serena, La Serena 1700000, Chile
6
Departamento de Biología, Universidad de La Serena, La Serena 1700000, Chile
*
Author to whom correspondence should be addressed.
Academic Editor: Wilmore C. Webley
Received: 17 February 2017 / Revised: 19 May 2017 / Accepted: 23 May 2017 / Published: 30 May 2017
View Full-Text   |   Download PDF [762 KB, uploaded 30 May 2017]   |  

Abstract

The lethality of infectious diseases has decreased due to the implementation of crucial sanitary procedures such as vaccination. However, the resurgence of pathogenic diseases in different parts of the world has revealed the importance of identifying novel, rapid, and concrete solutions for control and prevention. Edible vaccines pose an interesting alternative that could overcome some of the constraints of traditional vaccines. The term “edible vaccine” refers to the use of edible parts of a plant that has been genetically modified to produce specific components of a particular pathogen to generate protection against a disease. The aim of this review is to present and critically examine “edible vaccines” as an option for global immunization against pathogenic diseases and their outbreaks and to discuss the necessary steps for their production and control and the list of plants that may already be used as edible vaccines. Additionally, this review discusses the required standards and ethical regulations as well as the advantages and disadvantages associated with this powerful biotechnology tool. View Full-Text
Keywords: edible vaccine; medicinal food; genetic modification; immunogenicity; disease outbreaks; food biotechnology edible vaccine; medicinal food; genetic modification; immunogenicity; disease outbreaks; food biotechnology
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MDPI and ACS Style

Concha, C.; Cañas, R.; Macuer, J.; Torres, M.J.; Herrada, A.A.; Jamett, F.; Ibáñez, C. Disease Prevention: An Opportunity to Expand Edible Plant-Based Vaccines? Vaccines 2017, 5, 14.

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