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Brain Sci. 2017, 7(2), 22; doi:10.3390/brainsci7020022

Physical Activity: A Viable Way to Reduce the Risks of Mild Cognitive Impairment, Alzheimer’s Disease, and Vascular Dementia in Older Adults

1
Department of Nutritional Sciences, The University of Arizona, Tucson, AZ 85721-0038, USA
2
Nishinomiya Kyoritsu Neurosurgical Hospital, Hyogo 663-8211, Japan
3
Department of Medicine, Vanderbilt University, Nashville, TN 37232-5280, USA
4
Chiba Prefectural University of Health Sciences, Chiba 261-0014, Japan
5
National Institute of Fitness & Sport in Kanoya, Kagoshima 891-2311, Japan
*
Author to whom correspondence should be addressed.
Academic Editor: Kamen Tsvetanov
Received: 30 November 2016 / Revised: 23 January 2017 / Accepted: 3 February 2017 / Published: 20 February 2017
(This article belongs to the Special Issue Risk and Protective Factors for Neurocognitive Aging)
View Full-Text   |   Download PDF [678 KB, uploaded 20 February 2017]   |  

Abstract

A recent alarming rise of neurodegenerative diseases in the developed world is one of the major medical issues affecting older adults. In this review, we provide information about the associations of physical activity (PA) with major age-related neurodegenerative diseases and syndromes, including Alzheimer’s disease, vascular dementia, and mild cognitive impairment. We also provide evidence of PA’s role in reducing the risks of these diseases and helping to improve cognitive outcomes in older adults. Finally, we describe some potential mechanisms by which this protective effect occurs, providing guidelines for future research. View Full-Text
Keywords: aging; Alzheimer’s disease; cognitive decline; dementia; health; mild cognitive impairment; physical activity aging; Alzheimer’s disease; cognitive decline; dementia; health; mild cognitive impairment; physical activity
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MDPI and ACS Style

Gallaway, P.J.; Miyake, H.; Buchowski, M.S.; Shimada, M.; Yoshitake, Y.; Kim, A.S.; Hongu, N. Physical Activity: A Viable Way to Reduce the Risks of Mild Cognitive Impairment, Alzheimer’s Disease, and Vascular Dementia in Older Adults. Brain Sci. 2017, 7, 22.

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