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Facilitation of Relational Learning in Schizophrenia
AbstractAbnormal hippocampal function likely contributes to relational learning deficits observed in schizophrenia. It is unknown whether these deficits can be attenuated with a training intervention. The purpose of this project was to determine if training could facilitate relational learning of the transverse patterning task in schizophrenia. Healthy and schizophrenia subjects completed a version of transverse patterning that incorporated training. The majority of subjects with schizophrenia successfully learned transverse patterning when provided with training. A subgroup (approximately 25%) of schizophrenia subjects showed no tendency to learn with training. These results were replicated in a second study with a separate cohort and different stimuli. This study illustrates that relational learning of the transverse patterning can be facilitated in schizophrenia with training.
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Spieker, E.A.; Griego, J.A.; Astur, R.S.; Holcomb, H.H.; Rowland, L.M. Facilitation of Relational Learning in Schizophrenia. Behav. Sci. 2013, 3, 206-216.View more citation formats
Spieker EA, Griego JA, Astur RS, Holcomb HH, Rowland LM. Facilitation of Relational Learning in Schizophrenia. Behavioral Sciences. 2013; 3(2):206-216.Chicago/Turabian Style
Spieker, Elena A.; Griego, Jacqueline A.; Astur, Robert S.; Holcomb, Henry H.; Rowland, Laura M. 2013. "Facilitation of Relational Learning in Schizophrenia." Behav. Sci. 3, no. 2: 206-216.