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Pathogens 2014, 3(3), 549-562; doi:10.3390/pathogens3030549

Host Pathogen Relations: Exploring Animal Models for Fungal Pathogens

Biology and Biotechnology Department, Worcester Polytechnic University, Worcester, MA 01605, USA
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Received: 8 April 2014 / Revised: 18 June 2014 / Accepted: 23 June 2014 / Published: 30 June 2014
(This article belongs to the Special Issue Animal Model to Study Viral Immunity)
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Abstract

Pathogenic fungi cause superficial infections but pose a significant public health risk when infections spread to deeper tissues, such as the lung. Within the last three decades, fungi have been identified as the leading cause of nosocomial infections making them the focus of research. This review outlines the model systems such as the mouse, zebrafish larvae, flies, and nematodes, as well as ex vivo and in vitro systems available to study common fungal pathogens. View Full-Text
Keywords: fungal pathogens; Candida; Cryptococcus; Histoplasma; Aspergillus; model host systems fungal pathogens; Candida; Cryptococcus; Histoplasma; Aspergillus; model host systems
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Harwood, C.G.; Rao, R.P. Host Pathogen Relations: Exploring Animal Models for Fungal Pathogens. Pathogens 2014, 3, 549-562.

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