Synergism and Mutualism in Non-Enzymatic RNA Polymerization
Abstract
:1. Introduction
2. Non-Enzymatic RNA Polymerization
3. The RNA World Hypothesis
4. Thermodynamics of RNA Polymerization
5. Chemical Activation of Mononucleotides
6. Non-Enzymatic RNA Oligomerization
6.1. Mineral-Catalyzed RNA Oligomerization
6.1.1. Effect of Salts, Temperature and pH
6.1.2. Mechanism of Catalysis by Montmorillonite
6.1.3. Effect of Other Minerals
6.2. Lipid-Catalyzed RNA Oligomerization
6.3. “Click Chemistry-Like” RNA Oligomerization in Water
6.4. Peptide-Catalyzed RNA Oligomerization in Eutectic Phase
6.5. Discussion of the Results of Non-Enzymatic RNA Oligomerization
7. A Proposed Experimental Model
8. Concluding Remarks
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Kaddour, H.; Sahai, N. Synergism and Mutualism in Non-Enzymatic RNA Polymerization. Life 2014, 4, 598-620. https://doi.org/10.3390/life4040598
Kaddour H, Sahai N. Synergism and Mutualism in Non-Enzymatic RNA Polymerization. Life. 2014; 4(4):598-620. https://doi.org/10.3390/life4040598
Chicago/Turabian StyleKaddour, Hussein, and Nita Sahai. 2014. "Synergism and Mutualism in Non-Enzymatic RNA Polymerization" Life 4, no. 4: 598-620. https://doi.org/10.3390/life4040598