Next Article in Journal
Intercompartmental Piecewise Gene Transfer
Next Article in Special Issue
The History of Tree and Shrub Taxa on Bol'shoy Lyakhovsky Island (New Siberian Archipelago) since the Last Interglacial Uncovered by Sedimentary Ancient DNA and Pollen Data
Previous Article in Journal
Expression Profiling of Mitogen-Activated Protein Kinase Genes Reveals Their Evolutionary and Functional Diversity in Different Rubber Tree (Hevea brasiliensis) Cultivars
Previous Article in Special Issue
Optimized mtDNA Control Region Primer Extension Capture Analysis for Forensically Relevant Samples and Highly Compromised mtDNA of Different Age and Origin
Article Menu
Issue 10 (October) cover image

Export Article

Open AccessArticle
Genes 2017, 8(10), 262; doi:10.3390/genes8100262

Complete Mitochondrial Genome Sequencing of a Burial from a Romano–Christian Cemetery in the Dakhleh Oasis, Egypt: Preliminary Indications

1
Department of Anthropology, Western University, London, ON N6A 3K7, Canada
2
Armed Forces Medical Examiner System—Armed Forces DNA Identification Laboratory (AFMES/AFDIL), Dover, DE 19902, USA
3
Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
4
Department of Anthropology, University of Illinois at Urbana-Champaign, 109 Davenport Hall, 607 S. Mathews Ave, Urbana, IL 61801, USA & Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
5
Department of Anthropology, Lakehead University, Thunder Bay, ON P7B 5E1, Canada
Current address: FBI Laboratory, 2501 Investigation Parkway, Quantico, VA 22135, USA.
*
Author to whom correspondence should be addressed.
Academic Editor: Michael Hofreiter
Received: 16 June 2017 / Revised: 15 September 2017 / Accepted: 26 September 2017 / Published: 6 October 2017
(This article belongs to the Special Issue Novel and Neglected Areas of Ancient DNA Research)
View Full-Text   |   Download PDF [914 KB, uploaded 11 October 2017]   |  

Abstract

The curse of ancient Egyptian DNA was lifted by a recent study which sequenced the mitochondrial genomes (mtGenome) of 90 ancient Egyptians from the archaeological site of Abusir el-Meleq. Surprisingly, these ancient inhabitants were more closely related to those from the Near East than to contemporary Egyptians. It has been accepted that the timeless highway of the Nile River seeded Egypt with African genetic influence, well before pre-Dynastic times. Here we report on the successful recovery and analysis of the complete mtGenome from a burial recovered from a remote Romano–Christian cemetery, Kellis 2 (K2). K2 serviced the ancient municipality of Kellis, a village located in the Dakhleh Oasis in the southwest desert in Egypt. The data were obtained by high throughput sequencing (HTS) performed independently at two ancient DNA facilities (Armed Forces DNA Identification Laboratory, Dover, DE, USA and Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA). These efforts produced concordant haplotypes representing a U1a1a haplogroup lineage. This result indicates that Near Eastern maternal influence previously identified at Abusir el-Meleq was also present further south, in ancient Kellis during the Romano–Christian period. View Full-Text
Keywords: Dakhleh Oasis; mitochondrial genome; Egypt; high throughput sequencing; U1a1a haplogroup; ancient DNA Dakhleh Oasis; mitochondrial genome; Egypt; high throughput sequencing; U1a1a haplogroup; ancient DNA
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Molto, J.E.; Loreille, O.; Mallott, E.K.; Malhi, R.S.; Fast, S.; Daniels-Higginbotham, J.; Marshall, C.; Parr, R. Complete Mitochondrial Genome Sequencing of a Burial from a Romano–Christian Cemetery in the Dakhleh Oasis, Egypt: Preliminary Indications. Genes 2017, 8, 262.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Genes EISSN 2073-4425 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top