Genes 2011, 2(3), 640-660; doi:10.3390/genes2030640
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Genes Involved in the Production of Antimetabolite Toxins by Pseudomonas syringae Pathovars

1 Experimental Station La Mayora, Institute of Subtropical Horticulture and Mediterranean “La Mayora” (IHSM-UMA-CSIC), Algarrobo-Costa (Málaga) 29750, Spain 2 Microbiology Department, Institute of Subtropical Horticultural and Mediterranean “La Mayora” (IHSM-UMA-CSIC), Faculty of Science, University of Málaga, Associated Unit with the CSIC, Campus de Teatinos, Málaga 29071, Spain
* Author to whom correspondence should be addressed.
Received: 16 August 2011; in revised form: 6 September 2011 / Accepted: 6 September 2011 / Published: 15 September 2011
(This article belongs to the Special Issue Genes and Genomes of Plant Pathogenic Bacteria)
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Abstract: Pseudomonas syringae is pathogenic in a wide variety of plants, causing diseases with economic impacts. Pseudomonas syringae pathovars produce several toxins that can function as virulence factors and contribute to disease symptoms. These virulence factors include antimetabolite toxins, such as tabtoxin, phaseolotoxin and mangotoxin, which target enzymes in the pathways of amino acid metabolism. The antimetabolite toxins are generally located in gene clusters present in the flexible genomes of specific strains. These gene clusters are typically present in blocks of genes that appear to be integrated into specific sites in the P. syringae core genome. A general overview of the genetic organization and biosynthetic and regulatory functions of these genetic traits of the antimetabolite toxins will be given in the present work.
Keywords: secondary metabolite; gene cluster; tabtoxin; phaseolotoxin; mangotoxin; phytotoxin

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MDPI and ACS Style

Arrebola, E.; Cazorla, F.M.; Pérez-García, A.; Vicente, A. Genes Involved in the Production of Antimetabolite Toxins by Pseudomonas syringae Pathovars. Genes 2011, 2, 640-660.

AMA Style

Arrebola E, Cazorla FM, Pérez-García A, Vicente A. Genes Involved in the Production of Antimetabolite Toxins by Pseudomonas syringae Pathovars. Genes. 2011; 2(3):640-660.

Chicago/Turabian Style

Arrebola, Eva; Cazorla, Francisco M; Pérez-García, Alejandro; Vicente, Antonio de. 2011. "Genes Involved in the Production of Antimetabolite Toxins by Pseudomonas syringae Pathovars." Genes 2, no. 3: 640-660.

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