Cancers 2010, 2(1), 114-132; doi:10.3390/cancers2010114

Angiogenesis and Melanoma

Department of Human Anatomy and Histology, University of Bari Medical School, Piazza G. Cesare, 11, Policlinico 70124, Bari, Italy
* Author to whom correspondence should be addressed.
Received: 11 January 2010; in revised form: 10 February 2010 / Accepted: 24 February 2010 / Published: 25 February 2010
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Abstract: Angiogenesis occurs in pathological conditions, such as tumors, where a specific critical point in tumor progression is the transition from the avascular to the vascular phase. Tumor angiogenesis depends mainly on the release by neoplastic cells of growth factors specific for endothelial cells, which are able to stimulate the growth of the host’s blood vessels. This article summarizes the literature concerning the relationship between angiogenesis and human melanoma progression. The recent applications of antiangiogenic agents which interfere with melanoma progression are also described.
Keywords: angiogenesis; antiangiogenesis; human melanoma; tumor progression

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MDPI and ACS Style

Ribatti, D.; Annese, T.; Longo, V. Angiogenesis and Melanoma. Cancers 2010, 2, 114-132.

AMA Style

Ribatti D, Annese T, Longo V. Angiogenesis and Melanoma. Cancers. 2010; 2(1):114-132.

Chicago/Turabian Style

Ribatti, Domenico; Annese, Tiziana; Longo, Vito. 2010. "Angiogenesis and Melanoma." Cancers 2, no. 1: 114-132.

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