Next Article in Journal
Thermoelectric Responsive Shape Memory Graphene/Hydro-Epoxy Composites for Actuators
Next Article in Special Issue
Neural Circuits on a Chip
Previous Article in Journal
Design, Analysis, and Verification of Ka-Band Pattern Reconfigurable Patch Antenna Using RF MEMS Switches
Article Menu

Export Article

Open AccessFeature PaperArticle
Micromachines 2016, 7(8), 146; doi:10.3390/mi7080146

Microfluidic Neurons, a New Way in Neuromorphic Engineering?

LIMMS (Laboratory for Integrated Micro Mechatronic Systems)/CNRS-IIS (Institute of Industrial Science), The University of Tokyo, 4-6-1 Komaba, Meguroku, 153-8505 Tokyo, Japan
*
Author to whom correspondence should be addressed.
Academic Editor: Nikos Chronis
Received: 20 July 2016 / Revised: 14 August 2016 / Accepted: 18 August 2016 / Published: 22 August 2016
(This article belongs to the Special Issue MEMS/NEMS for Neuroscience)
View Full-Text   |   Download PDF [5529 KB, uploaded 22 August 2016]   |  

Abstract

This article describes a new way to explore neuromorphic engineering, the biomimetic artificial neuron using microfluidic techniques. This new device could replace silicon neurons and solve the issues of biocompatibility and power consumption. The biological neuron transmits electrical signals based on ion flow through their plasma membrane. Action potentials are propagated along axons and represent the fundamental electrical signals by which information are transmitted from one place to another in the nervous system. Based on this physiological behavior, we propose a microfluidic structure composed of chambers representing the intra and extracellular environments, connected by channels actuated by Quake valves. These channels are equipped with selective ion permeable membranes to mimic the exchange of chemical species found in the biological neuron. A thick polydimethylsiloxane (PDMS) membrane is used to create the Quake valve membrane. Integrated electrodes are used to measure the potential difference between the intracellular and extracellular environments: the membrane potential. View Full-Text
Keywords: biomimetic artificial neuron; microfluidic; action potential biomimetic artificial neuron; microfluidic; action potential
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Levi, T.; Fujii, T. Microfluidic Neurons, a New Way in Neuromorphic Engineering? Micromachines 2016, 7, 146.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Micromachines EISSN 2072-666X Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top