Fabrication of a Cell Fixation Device for Robotic Cell Microinjection
AbstractAutomation of cell microinjection greatly reduces operational difficulty, but cell fixation remains a challenge. Here, we describe an innovative device that solves the fixation problem without single-cell operation. The microarray cylinder is designed with a polydimethylsiloxane (PDMS) material surface to control the contact force between cells and the material. Data show that when the injection velocity exceeds 1.5 mm/s, microinjection success rate is over 80%. The maximum value of the adhesion force between the PDMS plate and the cell is 0.0138 N, and the need can be met in practical use of the robotic microinjection. View Full-Text
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Xie, Y.; Zhou, Y.; Xi, W.; Zeng, F.; Chen, S. Fabrication of a Cell Fixation Device for Robotic Cell Microinjection. Micromachines 2016, 7, 131.
Xie Y, Zhou Y, Xi W, Zeng F, Chen S. Fabrication of a Cell Fixation Device for Robotic Cell Microinjection. Micromachines. 2016; 7(8):131.Chicago/Turabian Style
Xie, Yu; Zhou, Yunlei; Xi, Wenming; Zeng, Feng; Chen, Songyue. 2016. "Fabrication of a Cell Fixation Device for Robotic Cell Microinjection." Micromachines 7, no. 8: 131.
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