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Micromachines 2015, 6(4), 462-472; doi:10.3390/mi6040462

A Fast Colourimetric Assay for Lead Detection Using Label-Free Gold Nanoparticles (AuNPs)

1
Department of Civil Engineering, McGill University, Montreal, QC H3A 0C3, Canada
2
Department of Mechanical Engineering, McGill University, Montreal, QC H3A 0C3, Canada
*
Authors to whom correspondence should be addressed.
Academic Editor: Fan-Gang Tseng
Received: 31 December 2014 / Revised: 27 March 2015 / Accepted: 15 April 2015 / Published: 22 April 2015
(This article belongs to the Special Issue Biomedical Microdevices)
View Full-Text   |   Download PDF [1696 KB, uploaded 22 April 2015]   |  

Abstract

A sensitive colourimetric method for lead (PbII) detection is reported in this paper using a common tripeptide, glutathione (GSH), and label-free gold nanoparticles (AuNPs). A limit of detection of 6.0 ppb in water was achieved and the dynamic linear range was up to 500 ppb. Selectivity over fourteen potential interfering metal ions was tested and most of these metal ions do not interfere with the method. View Full-Text
Keywords: gold nanoparticle; label-free; lead; glutathione; colourimetric assay gold nanoparticle; label-free; lead; glutathione; colourimetric assay
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Zhong, G.; Liu, J.; Liu, X. A Fast Colourimetric Assay for Lead Detection Using Label-Free Gold Nanoparticles (AuNPs). Micromachines 2015, 6, 462-472.

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