Micromachines 2012, 3(4), 615-631; doi:10.3390/mi3040615
Review

Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications

1, 1, 1, 2 and 1,* email
Received: 13 September 2012; in revised form: 2 November 2012 / Accepted: 7 November 2012 / Published: 14 November 2012
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Despite the advancements made in drug delivery systems over the years, many challenges remain in drug delivery systems for treating chronic diseases at the personalized medicine level. The current urgent need is to develop novel strategies for targeted therapy of chronic diseases. Due to their unique properties, microelectromechanical systems (MEMS) technology has been recently engineered as implantable drug delivery systems for disease therapy. This review examines the challenges faced in implementing implantable MEMS drug delivery systems in vivo and the solutions available to overcome these challenges.
Keywords: MEMS device; drug delivery; biomedical applications; implantable
PDF Full-text Download PDF Full-Text [1298 KB, uploaded 14 November 2012 10:04 CET]

Export to BibTeX |
EndNote


MDPI and ACS Style

Tng, D.J.H.; Hu, R.; Song, P.; Roy, I.; Yong, K.-T. Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications. Micromachines 2012, 3, 615-631.

AMA Style

Tng DJH, Hu R, Song P, Roy I, Yong K-T. Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications. Micromachines. 2012; 3(4):615-631.

Chicago/Turabian Style

Tng, Danny J.H.; Hu, Rui; Song, Peiyi; Roy, Indrajit; Yong, Ken-Tye. 2012. "Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications." Micromachines 3, no. 4: 615-631.

Micromachines EISSN 2072-666X Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert