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Integrated Biophotonics with CYTOP
Department of Physics, Science Institute, University of Iceland, Dunhagi 3, IS107 Reykjavik, Iceland
Department of Applied Physics, Chalmers University of Technology, SE-41296 Gothenburg, Sweden
* Author to whom correspondence should be addressed.
Received: 24 January 2012; in revised form: 16 February 2012 / Accepted: 20 February 2012 / Published: 29 February 2012
Abstract: We describe how the amorphous fluoropolymer CYTOP can be advantageously used as a waveguide cladding material in integrated optical circuits suitable for applications in integrated biophotonics. The unique refractive index of CYTOP (n = 1.34) enables the cladding material to be well index-matched to an optically probed sample solution. Furthermore, ultra-high index contrast waveguides can be fabricated, using conventional optical polymers as waveguide core materials, offering a route to large-scale integration of optical functions on a single chip. We discuss applications of this platform to evanescent-wave excitation fluorescence microscopy, passive and/or thermo-electrically-controlled on-chip light manipulation, on-chip light generation, and direct integration with microfluidic circuits through low-temperature bonding.
Keywords: lab-on-a-chip; fluorescence microscopy; integrated biophotonics; polymer waveguides; fluoropolymers; biosensors; microfluidics
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MDPI and ACS Style
Leosson, K.; Agnarsson, B. Integrated Biophotonics with CYTOP. Micromachines 2012, 3, 114-125.
Leosson K, Agnarsson B. Integrated Biophotonics with CYTOP. Micromachines. 2012; 3(1):114-125.
Leosson, Kristjan; Agnarsson, Björn. 2012. "Integrated Biophotonics with CYTOP." Micromachines 3, no. 1: 114-125.