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Micromachines 2012, 3(1), 114-125; doi:10.3390/mi3010114
Article

Integrated Biophotonics with CYTOP

1,*  and 2
1 Department of Physics, Science Institute, University of Iceland, Dunhagi 3, IS107 Reykjavik, Iceland 2 Department of Applied Physics, Chalmers University of Technology, SE-41296 Gothenburg, Sweden
* Author to whom correspondence should be addressed.
Received: 24 January 2012 / Revised: 16 February 2012 / Accepted: 20 February 2012 / Published: 29 February 2012
(This article belongs to the Special Issue Nano-photonic Devices)
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Abstract

We describe how the amorphous fluoropolymer CYTOP can be advantageously used as a waveguide cladding material in integrated optical circuits suitable for applications in integrated biophotonics. The unique refractive index of CYTOP (n = 1.34) enables the cladding material to be well index-matched to an optically probed sample solution. Furthermore, ultra-high index contrast waveguides can be fabricated, using conventional optical polymers as waveguide core materials, offering a route to large-scale integration of optical functions on a single chip. We discuss applications of this platform to evanescent-wave excitation fluorescence microscopy, passive and/or thermo-electrically-controlled on-chip light manipulation, on-chip light generation, and direct integration with microfluidic circuits through low-temperature bonding.
Keywords: lab-on-a-chip; fluorescence microscopy; integrated biophotonics; polymer waveguides; fluoropolymers; biosensors; microfluidics lab-on-a-chip; fluorescence microscopy; integrated biophotonics; polymer waveguides; fluoropolymers; biosensors; microfluidics
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Leosson, K.; Agnarsson, B. Integrated Biophotonics with CYTOP. Micromachines 2012, 3, 114-125.

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