Next Article in Journal / Special Issue
Topographic Relationship between the Supratrochlear Nerve and Corrugator Supercilii Muscle—Can This Anatomical Knowledge Improve the Response to Botulinum Toxin Injections in Chronic Migraine?
Previous Article in Journal
Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor
Previous Article in Special Issue
Onabotulinumtoxin A Treatment of Drooling in Children with Cerebral Palsy: A Prospective, Longitudinal Open-Label Study
Article Menu

Export Article

Open AccessReview
Toxins 2015, 7(7), 2615-2628; doi:10.3390/toxins7072615

Treatment of Chronic Migraine with Focus on Botulinum Neurotoxins

Department of Neurology, Yale University, 20 York St., New Haven, CT 06510, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Michel R. Popoff
Received: 1 June 2015 / Revised: 2 July 2015 / Accepted: 8 July 2015 / Published: 14 July 2015
(This article belongs to the Collection Botulinum Toxins on Human Pain)
View Full-Text   |   Download PDF [959 KB, uploaded 14 July 2015]   |  

Abstract

Migraine is the most common neurological disorder, and contributes to disability and large healthcare costs in the United States and the world. The treatment of migraine until recently has focused on medications, both abortive and prophylactic, but treatment of chronic migraine has been revolutionized with the introduction of botulinum toxin injection therapy. In this review, we explore the current understanding of migraine pathophysiology, and the evolution of the use of botulinum toxin therapy including proposed pathophysiological mechanisms through animal data. We also discuss the similarities and differences between three injection techniques. View Full-Text
Keywords: botulinum toxin; migraine; headache; chronic migraine; chronic daily headache; neurotoxins; medication overuse headache botulinum toxin; migraine; headache; chronic migraine; chronic daily headache; neurotoxins; medication overuse headache
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Schaefer, S.M.; Gottschalk, C.H.; Jabbari, B. Treatment of Chronic Migraine with Focus on Botulinum Neurotoxins. Toxins 2015, 7, 2615-2628.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Toxins EISSN 2072-6651 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top