Next Article in Journal
DXD Motif-Dependent and -Independent Effects of the Chlamydia trachomatis Cytotoxin CT166
Previous Article in Journal
Dual Effects Exerted in Vitro by Micromolar Concentrations of Deoxynivalenol on Undifferentiated Caco-2 Cells
Article Menu

Export Article

Open AccessArticle
Toxins 2015, 7(2), 604-620; doi:10.3390/toxins7020604

Altered Gene Expression Profiles of Wheat Genotypes against Fusarium Head Blight

Kihara Institute for Biological Research, Yokohama City University, Maioka 641-12, Totsuka, Yokohama 244-0813, Japan
Vascular Biology Laboratory, Heart Institute (InCor), University of Sao Paulo, School of Medicine, Av. Eneas C Aguiar, 44-Annex 2, 9th floor, Sao Paulo 05403-900, Brazil
National Food Research Institute, National Agriculture and Food Research Organization, 2-1-12 Kannondai, Tsukuba 305-8642, Japan
Author to whom correspondence should be addressed.
Academic Editor: Antonio Moretti
Received: 30 December 2014 / Revised: 3 February 2015 / Accepted: 10 February 2015 / Published: 16 February 2015
(This article belongs to the Section Mycotoxins)
View Full-Text   |   Download PDF [1626 KB, uploaded 16 February 2015]   |  


Fusarium graminearum is responsible for Fusarium head blight (FHB), which is a destructive disease of wheat that makes its quality unsuitable for end use. To understand the temporal molecular response against this pathogen, microarray gene expression analysis was carried out at two time points on three wheat genotypes, the spikes of which were infected by Fusarium graminearum. The greatest number of genes was upregulated in Nobeokabouzu-komugi followed by Sumai 3, whereas the minimum expression in Gamenya was at three days after inoculation (dai). In Nobeokabouzu-komugi, high expression of detoxification genes, such as multidrug-resistant protein, multidrug resistance-associated protein, UDP-glycosyltransferase and ABC transporters, in addition to systemic defense-related genes, were identified at the early stage of infection. This early response of the highly-resistant genotype implies a different resistance response from the other resistant genotype, Sumai 3, primarily containing local defense-related genes, such as cell wall defense genes. In Gamenya, the expression of all three functional groups was minimal. The differences in these molecular responses with respect to the time points confirmed the variation in the genotypes. For the first time, we report the nature of gene expression in the FHB-highly resistant cv. Nobeokabouzu-komugi during the disease establishment stage and the possible underlying molecular response. View Full-Text
Keywords: wheat; Fusarium graminearum; microarray; molecular response; detoxification; local and systemic response wheat; Fusarium graminearum; microarray; molecular response; detoxification; local and systemic response

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary materials

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Kosaka, A.; Manickavelu, A.; Kajihara, D.; Nakagawa, H.; Ban, T. Altered Gene Expression Profiles of Wheat Genotypes against Fusarium Head Blight. Toxins 2015, 7, 604-620.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Toxins EISSN 2072-6651 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top