Toxins 2015, 7(11), 4758-4772; doi:10.3390/toxins7114758
The Protective Effect of Bee Venom on Fibrosis Causing Inflammatory Diseases
1
Department of Pathology, College of Medicine, Catholic University of Daegu, 3056-6, Daemyung-4-Dong, Nam-gu, Daegu 705-718, Korea
2
School of Biomedical Sciences, Charles Sturt University, Panorama Avenue, Bathurst, NSW 2795, Australia
*
Author to whom correspondence should be addressed.
Academic Editor: Ren Lai
Received: 14 August 2015 / Revised: 24 October 2015 / Accepted: 5 November 2015 / Published: 16 November 2015
(This article belongs to the Special Issue Bee and Wasp Venoms: Biological Characteristics and Therapeutic Application)
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Abstract
Bee venom therapy is a treatment modality that may be thousands of years old and involves the application of live bee stings to the patient’s skin or, in more recent years, the injection of bee venom into the skin with a hypodermic needle. Studies have proven the effectiveness of bee venom in treating pathological conditions such as arthritis, pain and cancerous tumors. However, there has not been sufficient review to fully elucidate the cellular mechanisms of the anti-inflammatory effects of bee venom and its components. In this respect, the present study reviews current understanding of the mechanisms of the anti-inflammatory properties of bee venom and its components in the treatment of liver fibrosis, atherosclerosis and skin disease. View Full-TextKeywords:
bee venom; inflammation; liver fibrosis; atherosclerosis; skin disease
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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MDPI and ACS Style
Lee, W.-R.; Pak, S.C.; Park, K.-K. The Protective Effect of Bee Venom on Fibrosis Causing Inflammatory Diseases. Toxins 2015, 7, 4758-4772.
