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Trichothecenes: From Simple to Complex Mycotoxins
Bacterial Foodborne Pathogens and Mycology, National Center for Agricultural Utilization Research, U.S. Department of Agriculture-Agriculture Research Service, Peoria, IL 61604, USA
Biology Department, Bradley University, Peoria, IL 61625, USA
* Author to whom correspondence should be addressed.
Received: 26 May 2011; in revised form: 10 June 2011 / Accepted: 29 June 2011 / Published: 1 July 2011
Abstract: As the world’s population grows, access to a safe food supply will continue to be a global priority. In recent years, the world has experienced an increase in mycotoxin contamination of grains due to climatic and agronomic changes that encourage fungal growth during cultivation. A number of the molds that are plant pathogens produce trichothecene mycotoxins, which are known to cause serious human and animal toxicoses. This review covers the types of trichothecenes, their complexity, and proposed biosynthetic pathways of trichothecenes.
Keywords: trichothecenes; mycotoxins; Type A; Type B; macrocyclic; d-type; t-type; toxin biosynthesis
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Cite This Article
MDPI and ACS Style
McCormick, S.P.; Stanley, A.M.; Stover, N.A.; Alexander, N.J. Trichothecenes: From Simple to Complex Mycotoxins. Toxins 2011, 3, 802-814.
McCormick SP, Stanley AM, Stover NA, Alexander NJ. Trichothecenes: From Simple to Complex Mycotoxins. Toxins. 2011; 3(7):802-814.
McCormick, Susan P.; Stanley, April M.; Stover, Nicholas A.; Alexander, Nancy J. 2011. "Trichothecenes: From Simple to Complex Mycotoxins." Toxins 3, no. 7: 802-814.