Next Article in Journal
Phytochemicals in Cancer Prevention and Therapy: Truth or Dare?
Next Article in Special Issue
Fibrolase: Trials and Tribulations
Previous Article in Journal
Ochratoxin A: General Overview and Actual Molecular Status
Previous Article in Special Issue
Inhibition of Hemorragic Snake Venom Components: Old and New Approaches
Toxins 2010, 2(4), 494-516; doi:10.3390/toxins2040494
Review

Venom Proteins of the Parasitoid Wasp Nasonia vitripennis: Recent Discovery of an Untapped Pharmacopee

1,* , 2
 and 1
Received: 18 February 2010; in revised form: 22 March 2010 / Accepted: 24 March 2010 / Published: 30 March 2010
(This article belongs to the Special Issue Animal Venoms)
View Full-Text   |   Download PDF [642 KB, uploaded 30 March 2010]   |   Browse Figures
Abstract: Adult females of Nasonia vitripennis inject a venomous mixture into its host flies prior to oviposition. Recently, the entire genome of this ectoparasitoid wasp was sequenced, enabling the identification of 79 venom proteins. The next challenge will be to unravel their specific functions, but based on homolog studies, some predictions already can be made. Parasitization has an enormous impact on hosts physiology of which five major effects are discussed in this review: the impact on immune responses, induction of developmental arrest, increases in lipid levels, apoptosis and nutrient releases. The value of deciphering this venom is also discussed.
Keywords: Nasonia; venom; immunity; phenoloxidase; coagulation; development; lipid; apoptosis; nutrient Nasonia; venom; immunity; phenoloxidase; coagulation; development; lipid; apoptosis; nutrient
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Danneels, E.L.; Rivers, D.B.; De Graaf, D.C. Venom Proteins of the Parasitoid Wasp Nasonia vitripennis: Recent Discovery of an Untapped Pharmacopee. Toxins 2010, 2, 494-516.

AMA Style

Danneels EL, Rivers DB, De Graaf DC. Venom Proteins of the Parasitoid Wasp Nasonia vitripennis: Recent Discovery of an Untapped Pharmacopee. Toxins. 2010; 2(4):494-516.

Chicago/Turabian Style

Danneels, Ellen L.; Rivers, David B.; De Graaf, Dirk C. 2010. "Venom Proteins of the Parasitoid Wasp Nasonia vitripennis: Recent Discovery of an Untapped Pharmacopee." Toxins 2, no. 4: 494-516.


Toxins EISSN 2072-6651 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert