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Toxins 2010, 2(4), 417-427; doi:10.3390/toxins2040417
Review

Inhibition of Hemorragic Snake Venom Components: Old and New Approaches

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Received: 4 March 2010; in revised form: 22 March 2010 / Accepted: 23 March 2010 / Published: 25 March 2010
(This article belongs to the Special Issue Animal Venoms)
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Abstract: Snake venoms are complex toxin mixtures. Viperidae and Crotalidae venoms, which are hemotoxic, are responsible for most of the envenomations around the world. Administration of antivenins aimed at the neutralization of toxins in humans is prone to potential risks. Neutralization of snake venom toxins has been achieved through different approaches: plant extracts have been utilized in etnomedicine. Direct electric current from low voltage showed neutralizing properties against venom phospholipase A2 and metalloproteases. This mini-review summarizes new achievements in venom key component inhibition. A deeper knowledge of alternative ways to inhibit venom toxins may provide supplemental treatments to serum therapy.
Keywords: antivenins; direct electric current; etnomedicine; metalloprotease; phospholipase A2; phosphodiesterase; snake venom antivenins; direct electric current; etnomedicine; metalloprotease; phospholipase A2; phosphodiesterase; snake venom
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Panfoli, I.; Calzia, D.; Ravera, S.; Morelli, A. Inhibition of Hemorragic Snake Venom Components: Old and New Approaches. Toxins 2010, 2, 417-427.

AMA Style

Panfoli I, Calzia D, Ravera S, Morelli A. Inhibition of Hemorragic Snake Venom Components: Old and New Approaches. Toxins. 2010; 2(4):417-427.

Chicago/Turabian Style

Panfoli, Isabella; Calzia, Daniela; Ravera, Silvia; Morelli, Alessandro. 2010. "Inhibition of Hemorragic Snake Venom Components: Old and New Approaches." Toxins 2, no. 4: 417-427.


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