Next Article in Journal
Lipidomic and Antioxidant Response to Grape Seed, Corn and Coconut Oils in Healthy Wistar Rats
Next Article in Special Issue
Maternal Low-Protein Diet Modulates Glucose Metabolism and Hepatic MicroRNAs Expression in the Early Life of Offspring †
Previous Article in Journal
Social Dysfunction and Diet Outcomes in People with Psychosis
Previous Article in Special Issue
The Effect of Selenium Supplementation on Glucose Homeostasis and the Expression of Genes Related to Glucose Metabolism
Article Menu
Issue 1 (January) cover image

Export Article

Open AccessArticle
Nutrients 2017, 9(1), 9; doi:10.3390/nu9010009

Nutrient Patterns Associated with Fasting Glucose and Glycated Haemoglobin Levels in a Black South African Population

1
Centre for Excellence in Nutrition, North-West University, Potchefstroom 2520, North West Province, South Africa
2
Wits Reproductive Health and HIV Institute, University of the Witwatersrand, Johannesburg 2000, South Africa
3
Division of Human Nutrition, Wageningen University, P.O. Box 17, 6700 AA Wageningen, The Netherlands
4
Medical Research Council Research Unit for Hypertension and Cardiovascular Disease, Faculty of Health Sciences, North-West University, Potchefstroom 2520, South Africa
*
Author to whom correspondence should be addressed.
Received: 27 September 2016 / Revised: 13 December 2016 / Accepted: 19 December 2016 / Published: 19 January 2017
(This article belongs to the Special Issue Nutrition and Diet Factors in Type 2 Diabetes)
View Full-Text   |   Download PDF [423 KB, uploaded 19 January 2017]   |  

Abstract

Type 2 diabetes (T2D) burden is increasing globally. However, evidence regarding nutrient patterns associated with the biomarkers of T2D is limited. This study set out to determine the nutrient patterns associated with fasting glucose and glycated haemoglobin the biomarkers of T2D. Factor analysis was used to derive nutrient patterns of 2010 participants stratified by urban/rural status and gender. Principal Component Analysis (PCA) was applied to 25 nutrients, computed from the quantified food frequency questionnaires (QFFQ). Three nutrient patterns per stratum, which accounted for 73% of the variation of the selected nutrients, were identified. Multivariate linear regression models adjusted for age, BMI, smoking, physical activity, education attained, alcohol intake, seasonality and total energy intake were computed. Starch, dietary fibre and B vitamins driven nutrient pattern was significantly associated with fasting glucose (β = −0.236 (−0.458; −0.014); p = 0.037) and glycated haemoglobin levels (β = −0.175 (−0.303; −0.047); p = 0.007) in rural women. Thiamine, zinc and plant protein driven nutrient pattern was associated with significant reductions in glycated haemoglobin and fasting glucose ((β = −0.288 (−0.543; −0.033); p = 0.027) and (β = −0.382 (−0.752; −0.012); p = 0.043), respectively) in rural men. Our results indicate that plant driven nutrient patterns are associated with low fasting glucose and glycated haemoglobin levels. View Full-Text
Keywords: plant based; fasting glucose and glycated haemoglobin; T2D; dietary patterns plant based; fasting glucose and glycated haemoglobin; T2D; dietary patterns
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Chikowore, T.; Pisa, P.T.; van Zyl, T.; Feskens, E.J.M.; Wentzel-Viljoen, E.; Conradie, K.R. Nutrient Patterns Associated with Fasting Glucose and Glycated Haemoglobin Levels in a Black South African Population. Nutrients 2017, 9, 9.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top