Next Article in Journal
Reviewing the Effects of l-Leucine Supplementation in the Regulation of Food Intake, Energy Balance, and Glucose Homeostasis
Next Article in Special Issue
Long-Term Supplementation with Beta Serum Concentrate (BSC), a Complex of Milk Lipids, during Post-Natal Brain Development Improves Memory in Rats
Previous Article in Journal
Fructose:Glucose Ratios—A Study of Sugar Self-Administration and Associated Neural and Physiological Responses in the Rat
Previous Article in Special Issue
Improved Blood Biomarkers but No Cognitive Effects from 16 Weeks of Multivitamin Supplementation in Healthy Older Adults
Article Menu

Export Article

Open AccessReview
Nutrients 2015, 7(5), 3891-3913; doi:10.3390/nu7053891

The Role of Gangliosides in Neurodevelopment

1
Centennial Dr, Whitianga 3510, New Zealand
2
Fonterra Co-operative Group Ltd., Private Bag 11029, Palmerston North 4442, New Zealand
3
Centre for Brain Research, Auckland University, Private Bag 92019, Auckland 1142, New Zealand
*
Author to whom correspondence should be addressed.
Received: 10 April 2015 / Revised: 4 May 2015 / Accepted: 8 May 2015 / Published: 22 May 2015
(This article belongs to the Special Issue Nutrition in Cognitive Function)
View Full-Text   |   Download PDF [547 KB, uploaded 25 May 2015]   |  

Abstract

Gangliosides are important components of neuronal cell membranes and it is widely accepted that they play a critical role in neuronal and brain development. They are functionally involved in neurotransmission and are thought to support the formation and stabilization of functional synapses and neural circuits required as the structural basis of memory and learning. Available evidence, as reviewed herein, suggests that dietary gangliosides may impact positively on cognitive functions, particularly in the early postnatal period when the brain is still growing. Further, new evidence suggests that the mechanism of action may be through an effect on the neuroplasticity of the brain, mediated through enhanced synaptic plasticity in the hippocampus and nigro-striatal dopaminergic pathway. View Full-Text
Keywords: gangliosides; brain; cognition; nutrition; neurodevelopment; neuroplasticity gangliosides; brain; cognition; nutrition; neurodevelopment; neuroplasticity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Palmano, K.; Rowan, A.; Guillermo, R.; Guan, J.; McJarrow, P. The Role of Gangliosides in Neurodevelopment. Nutrients 2015, 7, 3891-3913.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top