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Nutrients 2015, 7(5), 3154-3165; doi:10.3390/nu7053154

Enteral Nutrition in Pancreaticoduodenectomy: A Literature Review

1
School of Oncology and Experimental Surgery, University of Palermo, via Del Vespro 129, 90127 Palermo, Italy
2
Department of Surgical, Oncological and Dentistry Studies, University of Palermo, via Del Vespro 129, 90127 Palermo, Italy
3
Giaccone", University Hospital, School of Medicine, School of Biotechnology, University of Palermo, via Del Vespro 129, 90127 Palermo, Italy
4
School of Surgical Biotechnology and Regenerative Medicine in Organ Failure, University of Palermo, via Del Vespro 129, 90127 Palermo, Italy
5
School of Biotechnology, University of Palermo, via Del Vespro 129, 90127 Palermo, Italy
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Received: 30 November 2014 / Revised: 3 April 2015 / Accepted: 15 April 2015 / Published: 30 April 2015
(This article belongs to the Special Issue Recent Advances in Enteral Nutrition)
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Abstract

Pancreaticoduodenectomy (PD) is considered the gold standard treatment for periampullory carcinomas. This procedure presents 30%–40% of morbidity. Patients who have undergone pancreaticoduodenectomy often present perioperative malnutrition that is worse in the early postoperative days, affects the process of healing, the intestinal barrier function and the number of postoperative complications. Few studies focus on the relation between enteral nutrition (EN) and postoperative complications. Our aim was to perform a review, including only randomized controlled trial meta-analyses or well-designed studies, of evidence regarding the correlation between EN and main complications and outcomes after pancreaticoduodenectomy, as delayed gastric emptying (DGE), postoperative pancreatic fistula (POPF), postpancreatectomy hemorrhage (PPH), length of stay and infectious complications. Several studies, especially randomized controlled trial have shown that EN does not increase the rate of DGE. EN appeared safe and tolerated for patients after PD, even if it did not reveal any advantages in terms of POPF, PPH, length of stay and infectious complications. View Full-Text
Keywords: Enteral nutrition; pancreaticoduodenectomy; delayed gastric emptying; postoperative pancreatic fistula; postpancreatectomy hemorrhage Enteral nutrition; pancreaticoduodenectomy; delayed gastric emptying; postoperative pancreatic fistula; postpancreatectomy hemorrhage
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Buscemi, S.; Damiano, G.; Palumbo, V.D.; Spinelli, G.; Ficarella, S.; Monte, G.L.; Marrazzo, A.; Monte, A.I.L. Enteral Nutrition in Pancreaticoduodenectomy: A Literature Review. Nutrients 2015, 7, 3154-3165.

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