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Letter to the Editor Re: Comino, I., et al. Nutrients 2013, 5, 4250–4268
Nutrients 2013, 5(12), 4966-4977; doi:10.3390/nu5124966
Article

Changes in Blood Pressure and Lipid Levels in Young Women Consuming a Vitamin D-Fortified Skimmed Milk: A Randomised Controlled Trial

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Received: 15 October 2013; in revised form: 12 November 2013 / Accepted: 27 November 2013 / Published: 5 December 2013
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Abstract: Vitamin D exerts a variety of extra-skeletal functions. Aim: to know the effects of the consumption of a vitamin D-fortified skimmed milk on glucose, lipid profile, and blood pressure in young women. Methods: a randomised, placebo-controlled, double-blind parallel-group trial of 16 weeks duration was conducted in young women with low iron stores who consumed a skimmed milk fortified with iron and 200 IU/day (5 μg) of vitamin D (D-fortified group, n = 55), or a placebo without vitamin D (D-placebo group, n = 54). A reference group (n = 56) of iron-sufficient women was also recruited. Results: baseline serum 25-hydroxyvitamin D was inversely correlated with total-cholesterol (r = −0.176, p = 0.023) and low density lipoprotein-cholesterol (LDL-chol) (r = −0.176, p = 0.024). During the assay, LDL-cholesterol increased in the D-placebo group (p = 0.005) while it tended to decrease in the D-fortified group (p = 0.07). Neither group displayed changes in total-cholesterol, high density lipoprotein-cholesterol (HDL-chol), triglycerides or glucose levels. Systolic (p = 0.017) and diastolic (p = 0.010) blood pressure decreased during the assay in the D-fortified group without significant differences compared to the D-placebo. Conclusion: consumption of a dairy product fortified with vitamin D reduces systolic and diastolic blood pressure but does not change lipid levels in young women.
Keywords: vitamin D; food fortification; blood pressure; cholesterol; randomised controlled trial; women; dairy product vitamin D; food fortification; blood pressure; cholesterol; randomised controlled trial; women; dairy product
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Toxqui, L.; Blanco-Rojo, R.; Wright, I.; Pérez-Granados, A.M.; Vaquero, M.P. Changes in Blood Pressure and Lipid Levels in Young Women Consuming a Vitamin D-Fortified Skimmed Milk: A Randomised Controlled Trial. Nutrients 2013, 5, 4966-4977.

AMA Style

Toxqui L, Blanco-Rojo R, Wright I, Pérez-Granados AM, Vaquero MP. Changes in Blood Pressure and Lipid Levels in Young Women Consuming a Vitamin D-Fortified Skimmed Milk: A Randomised Controlled Trial. Nutrients. 2013; 5(12):4966-4977.

Chicago/Turabian Style

Toxqui, Laura; Blanco-Rojo, Ruth; Wright, Ione; Pérez-Granados, Ana M.; Vaquero, M. P. 2013. "Changes in Blood Pressure and Lipid Levels in Young Women Consuming a Vitamin D-Fortified Skimmed Milk: A Randomised Controlled Trial." Nutrients 5, no. 12: 4966-4977.


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