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Nutrients 2013, 5(11), 4380-4389; doi:10.3390/nu5114380
Article

Long-Term Consumption of Oats in Adult Celiac Disease Patients

1,2,3,* , 1,2
, 4
 and 5
Received: 29 August 2013; in revised form: 21 October 2013 / Accepted: 25 October 2013 / Published: 6 November 2013
(This article belongs to the Special Issue Nutrition and Celiac Disease)
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Abstract: Many celiac disease patients tolerate oats, but limited data are available on its long-term consumption. This was evaluated in the present study, focusing on small-bowel mucosal histology and gastrointestinal symptoms in celiac adults maintaining a strict gluten-free diet with or without oats. Altogether 106 long-term treated celiac adults were enrolled for this cross-sectional follow-up study. Daily consumption of oats and fiber was assessed, and small-bowel mucosal morphology and densities of CD3+, αβ+ and γσ+ intraepithelial lymphocytes determined. Gastrointestinal symptoms were assessed by a validated Gastrointestinal Symptom Rating Scale questionnaire. Seventy (66%) out of the 106 treated celiac disease patients had consumed a median of 20 g of oats (range 1–100 g) per day for up to eight years; all consumed oat products bought from general stores. Daily intake and long-term consumption of oats did not result in small-bowel mucosal villous damage, inflammation, or gastrointestinal symptoms. Oat-consumers had a significantly higher daily intake of fiber than those who did not use oats. Two thirds of celiac disease patients preferred to use oats in their daily diet. Even long-term ingestion of oats had no harmful effects.
Keywords: celiac disease; gluten-free diet; morphology; oats; questionnaire; small-bowel celiac disease; gluten-free diet; morphology; oats; questionnaire; small-bowel
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Kaukinen, K.; Collin, P.; Huhtala, H.; Mäki, M. Long-Term Consumption of Oats in Adult Celiac Disease Patients. Nutrients 2013, 5, 4380-4389.

AMA Style

Kaukinen K, Collin P, Huhtala H, Mäki M. Long-Term Consumption of Oats in Adult Celiac Disease Patients. Nutrients. 2013; 5(11):4380-4389.

Chicago/Turabian Style

Kaukinen, Katri; Collin, Pekka; Huhtala, Heini; Mäki, Markku. 2013. "Long-Term Consumption of Oats in Adult Celiac Disease Patients." Nutrients 5, no. 11: 4380-4389.


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