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Vitamin K Status in Chronic Kidney Disease
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON K7L 3V6, Canada
Department of Medicine, Queen's University, Kingston, ON K7L 3V6, Canada
* Author to whom correspondence should be addressed.
Received: 11 July 2013; in revised form: 17 October 2013 / Accepted: 31 October 2013 / Published: 7 November 2013
Abstract: The purpose of this review is to summarize the research to date on vitamin K status in chronic kidney disease (CKD). This review includes a summary of the data available on vitamin K status in patients across the spectrum of CKD as well as the link between vitamin K deficiency in CKD and bone dynamics, including mineralization and demineralization, as well as ectopic mineralization. It also describes two current clinical trials that are underway evaluating vitamin K treatment in CKD patients. These data may inform future clinical practice in this population.
Keywords: vitamin K; chronic kidney disease; renal insufficiency; vitamin K-dependent proteins
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MDPI and ACS Style
McCabe, K.M.; Adams, M.A.; Holden, R.M. Vitamin K Status in Chronic Kidney Disease. Nutrients 2013, 5, 4390-4398.
McCabe KM, Adams MA, Holden RM. Vitamin K Status in Chronic Kidney Disease. Nutrients. 2013; 5(11):4390-4398.
McCabe, Kristin M.; Adams, Michael A.; Holden, Rachel M. 2013. "Vitamin K Status in Chronic Kidney Disease." Nutrients 5, no. 11: 4390-4398.