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Nutrients 2013, 5(11), 4390-4398; doi:10.3390/nu5114390

Vitamin K Status in Chronic Kidney Disease

1
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON K7L 3V6, Canada
2
Department of Medicine, Queen's University, Kingston, ON K7L 3V6, Canada
*
Author to whom correspondence should be addressed.
Received: 11 July 2013 / Revised: 17 October 2013 / Accepted: 31 October 2013 / Published: 7 November 2013
(This article belongs to the Special Issue Vitamin K Nutrition and Metabolism)
View Full-Text   |   Download PDF [190 KB, uploaded 7 November 2013]

Abstract

The purpose of this review is to summarize the research to date on vitamin K status in chronic kidney disease (CKD). This review includes a summary of the data available on vitamin K status in patients across the spectrum of CKD as well as the link between vitamin K deficiency in CKD and bone dynamics, including mineralization and demineralization, as well as ectopic mineralization. It also describes two current clinical trials that are underway evaluating vitamin K treatment in CKD patients. These data may inform future clinical practice in this population. View Full-Text
Keywords: vitamin K; chronic kidney disease; renal insufficiency; vitamin K-dependent proteins vitamin K; chronic kidney disease; renal insufficiency; vitamin K-dependent proteins
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

McCabe, K.M.; Adams, M.A.; Holden, R.M. Vitamin K Status in Chronic Kidney Disease. Nutrients 2013, 5, 4390-4398.

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