Nutrients 2013, 5(10), 3854-3870; doi:10.3390/nu5103854
Review

Cocoa and Heart Health: A Historical Review of the Science

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Received: 15 July 2013; in revised form: 10 September 2013 / Accepted: 11 September 2013 / Published: 26 September 2013
(This article belongs to the Special Issue Chocolate and Cocoa in Human Health)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The medicinal use of cocoa has a long history dating back almost five hundred years when Hernán Cortés’s first experienced the drink in Mesoamerica. Doctors in Europe recommended the beverage to patients in the 1700s, and later American physicians followed suit and prescribed the drink in early America—ca. 1800s. This article delineates the historic trajectory of cocoa consumption, the linkage between cocoa’s bioactive-mechanistic properties, paying special attention to nitric oxides role in vasodilation of the arteries, to the current indicators purporting the benefits of cocoa and cardiovascular health.
Keywords: cocoa; heart-health; nitric oxide; cardiovascular disease; medical history
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MDPI and ACS Style

Pucciarelli, D.L. Cocoa and Heart Health: A Historical Review of the Science. Nutrients 2013, 5, 3854-3870.

AMA Style

Pucciarelli DL. Cocoa and Heart Health: A Historical Review of the Science. Nutrients. 2013; 5(10):3854-3870.

Chicago/Turabian Style

Pucciarelli, Deanna L. 2013. "Cocoa and Heart Health: A Historical Review of the Science." Nutrients 5, no. 10: 3854-3870.

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