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Maternal Vitamin D Status and Delivery by Cesarean
AbstractWe examined the association of vitamin D deficiency to risk of cesarean delivery using prospective data in a cohort of 1153 low income and minority gravidae. Circulating maternal 25-hydroxyvitamin D and intact parathyroid hormone were measured at entry to care 13.73 ± 5.6 weeks (mean ± SD). Intake of vitamin D and calcium was assessed at three time points during pregnancy. Using recent Institute of Medicine guidelines, 10.8% of the gravidae were at risk of vitamin D deficiency, and 23.8% at risk of insufficiency. Maternal 25-hydroxyvitamin D was related positively to vitamin D and calcium intakes and negatively to circulating concentrations of parathyroid hormone. Risk for cesarean delivery was increased significantly for vitamin D deficient women; there was no increased risk for gravidae at risk of insufficiency. When specific indications were examined, vitamin D deficiency was linked to a 2-fold increased risk of cesarean for prolonged labor. Results were the similar when prior guidelines for vitamin D deficiency (25(OH)D < 37.5nmol/L) and insufficiency (37.5–80 nmol/L) were utilized.
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Scholl, T.O.; Chen, X.; Stein, P. Maternal Vitamin D Status and Delivery by Cesarean. Nutrients 2012, 4, 319-330.View more citation formats
Scholl TO, Chen X, Stein P. Maternal Vitamin D Status and Delivery by Cesarean. Nutrients. 2012; 4(4):319-330.Chicago/Turabian Style
Scholl, Theresa O.; Chen, Xinhua; Stein, Peter. 2012. "Maternal Vitamin D Status and Delivery by Cesarean." Nutrients 4, no. 4: 319-330.