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Nutrients 2012, 4(11), 1622-1649; doi:10.3390/nu4111622
Review

Lipophilic Micronutrients and Adipose Tissue Biology

1,2,3,* , 1,2,3
 and 1,2,3
Received: 5 September 2012; in revised form: 6 October 2012 / Accepted: 27 October 2012 / Published: 6 November 2012
(This article belongs to the Special Issue Nutrigenetics and Nutrigenomics)
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Abstract: Lipophilic micronutrients (LM) constitute a large family of molecules including several vitamins (A, D, E, K) and carotenoids. Their ability to regulate gene expression is becoming increasingly clear and constitutes an important part of nutrigenomics. Interestingly, adipose tissue is not only a main storage site for these molecules within the body, but it is also subjected to the regulatory effects of LM. Indeed, several gene regulations have been described in adipose tissue that could strongly impact its biology with respect to the modulation of adipogenesis, inflammatory status, or energy homeostasis and metabolism, among others. The repercussions in terms of health effects of such regulations in the context of obesity and associated pathologies represent an exciting and emerging field of research. The present review will focus on the regulatory effects of vitamin A, D, E and K as well as carotenoids on adipose tissue biology and physiology, notably in the context of obesity and associated disorders.
Keywords: adipose tissue; adipocytes; vitamins; micronutrients; obesity; insulin resistance; inflammation; metabolism; adipogenesis adipose tissue; adipocytes; vitamins; micronutrients; obesity; insulin resistance; inflammation; metabolism; adipogenesis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Landrier, J.-F.; Marcotorchino, J.; Tourniaire, F. Lipophilic Micronutrients and Adipose Tissue Biology. Nutrients 2012, 4, 1622-1649.

AMA Style

Landrier J-F, Marcotorchino J, Tourniaire F. Lipophilic Micronutrients and Adipose Tissue Biology. Nutrients. 2012; 4(11):1622-1649.

Chicago/Turabian Style

Landrier, Jean-François; Marcotorchino, Julie; Tourniaire, Franck. 2012. "Lipophilic Micronutrients and Adipose Tissue Biology." Nutrients 4, no. 11: 1622-1649.


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