Next Article in Journal
Lipophilic Micronutrients and Adipose Tissue Biology
Next Article in Special Issue
Vitamin D — Effects on Skeletal and Extraskeletal Health and the Need for Supplementation
Previous Article in Journal
How Feasible Is Baby-Led Weaning as an Approach to Infant Feeding? A Review of the Evidence
Previous Article in Special Issue
Plant Calcium Content: Ready to Remodel
Article Menu

Export Article

Open AccessReview
Nutrients 2012, 4(11), 1610-1621; doi:10.3390/nu4111610

Vitamin D Interactions with Soy Isoflavones on Bone after Menopause: A Review

Department of Nutrition Science, Purdue University, 700 W State St, West Lafayette, IN 47907, USA
*
Author to whom correspondence should be addressed.
Received: 17 August 2012 / Revised: 26 October 2012 / Accepted: 30 October 2012 / Published: 6 November 2012
(This article belongs to the Special Issue Dietary Minerals)
View Full-Text   |   Download PDF [606 KB, uploaded 6 November 2012]   |  

Abstract

Vitamin D is known to increase Ca absorption in adults. However, the threshold vitamin D status to benefit Ca absorption is lower than the target vitamin D status for higher bone mineral density and lower fracture risk, pointing to another pathway for vitamin D to benefit bone. One possibility is by affecting osteoblast and osteoclasts directly. Vitamin D-related bone metabolism may also be affected by soy isoflavones, which selectively bind to the estrogen receptor β and may reduce bone loss in postmenopausal women. We discuss a possible synergistic effect of soy isoflavones and vitamin D on bone by affecting osteoblast and osteoclast formation and activity in postmenopausal women.
Keywords: vitamin D; phytoestrogen; soy isoflavones; bone; postmenopause vitamin D; phytoestrogen; soy isoflavones; bone; postmenopause
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Park, C.Y.; Weaver, C.M. Vitamin D Interactions with Soy Isoflavones on Bone after Menopause: A Review. Nutrients 2012, 4, 1610-1621.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top