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Vitamin D — Effects on Skeletal and Extraskeletal Health and the Need for Supplementation
AbstractVitamin D, the sunshine vitamin, has received a lot of attention recently as a result of a meteoric rise in the number of publications showing that vitamin D plays a crucial role in a plethora of physiological functions and associating vitamin D deficiency with many acute and chronic illnesses including disorders of calcium metabolism, autoimmune diseases, some cancers, type 2 diabetes mellitus, cardiovascular disease and infectious diseases. Vitamin D deficiency is now recognized as a global pandemic. The major cause for vitamin D deficiency is the lack of appreciation that sun exposure has been and continues to be the major source of vitamin D for children and adults of all ages. Vitamin D plays a crucial role in the development and maintenance of a healthy skeleton throughout life. There remains some controversy regarding what blood level of 25-hydroxyvitamin D should be attained for both bone health and reducing risk for vitamin D deficiency associated acute and chronic diseases and how much vitamin D should be supplemented.
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Wacker, M.; Holick, M.F. Vitamin D — Effects on Skeletal and Extraskeletal Health and the Need for Supplementation. Nutrients 2013, 5, 111-148.View more citation formats
Wacker M, Holick MF. Vitamin D — Effects on Skeletal and Extraskeletal Health and the Need for Supplementation. Nutrients. 2013; 5(1):111-148.Chicago/Turabian Style
Wacker, Matthias; Holick, Michael F. 2013. "Vitamin D — Effects on Skeletal and Extraskeletal Health and the Need for Supplementation." Nutrients 5, no. 1: 111-148.