Nutrients 2011, 3(4), 442-474; doi:10.3390/nu3040442
Review

Perspectives on Immunoglobulins in Colostrum and Milk

1,* email and 2email
Received: 2 March 2011; in revised form: 21 March 2011 / Accepted: 12 April 2011 / Published: 14 April 2011
(This article belongs to the Special Issue Dairy Nutrients)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Immunoglobulins form an important component of the immunological activity found in milk and colostrum. They are central to the immunological link that occurs when the mother transfers passive immunity to the offspring. The mechanism of transfer varies among mammalian species. Cattle provide a readily available immune rich colostrum and milk in large quantities, making those secretions important potential sources of immune products that may benefit humans. Immune milk is a term used to describe a range of products of the bovine mammary gland that have been tested against several human diseases. The use of colostrum or milk as a source of immunoglobulins, whether intended for the neonate of the species producing the secretion or for a different species, can be viewed in the context of the types of immunoglobulins in the secretion, the mechanisms by which the immunoglobulins are secreted, and the mechanisms by which the neonate or adult consuming the milk then gains immunological benefit. The stability of immunoglobulins as they undergo processing in the milk, or undergo digestion in the intestine, is an additional consideration for evaluating the value of milk immunoglobulins. This review summarizes the fundamental knowledge of immunoglobulins found in colostrum, milk, and immune milk.
Keywords: immunoglobulins; milk; colostrum; bovine; human; immunity; passive transfer
PDF Full-text Download PDF Full-Text [449 KB, uploaded 14 April 2011 14:01 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Hurley, W.L.; Theil, P.K. Perspectives on Immunoglobulins in Colostrum and Milk. Nutrients 2011, 3, 442-474.

AMA Style

Hurley WL, Theil PK. Perspectives on Immunoglobulins in Colostrum and Milk. Nutrients. 2011; 3(4):442-474.

Chicago/Turabian Style

Hurley, Walter L.; Theil, Peter K. 2011. "Perspectives on Immunoglobulins in Colostrum and Milk." Nutrients 3, no. 4: 442-474.

Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert