Pharmaceutics 2012, 4(1), 149-163; doi:10.3390/pharmaceutics4010149
Article

Probiotic Encapsulation Technology: From Microencapsulation to Release into the Gut

Gildas K. Gbassi 1,2  and Thierry Vandamme 1,* email
1 Laboratoire de Conception et Application de Molécules Bioactives (UMR-7199), Faculté de Pharmacie, UdS-CNRS, 74 Route du Rhin, 67401 Illkirch-Graffenstaden, France 2 Département de Chimie Générale et Minérale, Faculté de Pharmacie, Université de Cocody, 01 BPV 34, Abidjan, Cote d’Ivoire
* Author to whom correspondence should be addressed.
Received: 21 December 2011; in revised form: 20 January 2012 / Accepted: 31 January 2012 / Published: 6 February 2012
(This article belongs to the Special Issue Microencapsulation Technology Applied to Pharmaceutics)
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Abstract: Probiotic encapsulation technology (PET) has the potential to protect microorgansisms and to deliver them into the gut. Because of the promising preclinical and clinical results, probiotics have been incorporated into a range of products. However, there are still many challenges to overcome with respect to the microencapsulation process and the conditions prevailing in the gut. This paper reviews the methodological approach of probiotics encapsulation including biomaterials selection, choice of appropriate technology, in vitro release studies of encapsulated probiotics, and highlights the challenges to be overcome in this area.
Keywords: biomaterials; microencapsulation; probiotics; protective device; artificial media; cells release

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MDPI and ACS Style

Gbassi, G.K.; Vandamme, T. Probiotic Encapsulation Technology: From Microencapsulation to Release into the Gut. Pharmaceutics 2012, 4, 149-163.

AMA Style

Gbassi GK, Vandamme T. Probiotic Encapsulation Technology: From Microencapsulation to Release into the Gut. Pharmaceutics. 2012; 4(1):149-163.

Chicago/Turabian Style

Gbassi, Gildas K.; Vandamme, Thierry. 2012. "Probiotic Encapsulation Technology: From Microencapsulation to Release into the Gut." Pharmaceutics 4, no. 1: 149-163.

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