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Viruses 2014, 6(9), 3514-3534; doi:10.3390/v6093514

Role of microRNAs in Arbovirus/Vector Interactions

Australian Infectious Disease Research Centre, School of Biological Sciences, The University of Queensland, Brisbane, QLD 4072, Australia
Received: 28 July 2014 / Revised: 15 September 2014 / Accepted: 16 September 2014 / Published: 23 September 2014
(This article belongs to the Special Issue Interactions between Arboviruses and Arthropod Vectors)
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Abstract

The role of microRNAs (miRNAs) as small non-coding RNAs in regulation of gene expression has been recognized. They appear to be involved in regulation of a wide range of cellular pathways that affect several biological processes such as development, the immune system, survival, metabolism and host-pathogen interactions. Arthropod-borne viruses impose great economic and health risks around the world. Recent advances in miRNA biology have shed some light on the role of these small RNAs in vector-virus interactions. In this review, I will reflect on our current knowledge on the role of miRNAs in arbovirus-vector interactions and the potential avenues for their utilization in limiting virus replication and/or transmission. View Full-Text
Keywords: mosquito; arbovirus; gene regulation; microRNA mosquito; arbovirus; gene regulation; microRNA
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Asgari, S. Role of microRNAs in Arbovirus/Vector Interactions. Viruses 2014, 6, 3514-3534.

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