Viruses 2014, 6(5), 2122-2137; doi:10.3390/v6052122
Review

Oncolytic Virotherapy of Canine and Feline Cancer

1,2,* email, 1email, 1email, 2email, 1email and 1,2,3,* email
Received: 5 March 2014; in revised form: 22 April 2014 / Accepted: 30 April 2014 / Published: 16 May 2014
(This article belongs to the Section Antivirals & Vaccines)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Cancer is the leading cause of disease-related death in companion animals such as dogs and cats. Despite recent progress in the diagnosis and treatment of advanced canine and feline cancer, overall patient treatment outcome has not been substantially improved. Virotherapy using oncolytic viruses is one promising new strategy for cancer therapy. Oncolytic viruses (OVs) preferentially infect and lyse cancer cells, without causing excessive damage to surrounding healthy tissue, and initiate tumor-specific immunity. The current review describes the use of different oncolytic viruses for cancer therapy and their application to canine and feline cancer.
Keywords: cancer; canine and feline cancer therapy; oncolytic virus; oncolysis
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MDPI and ACS Style

Gentschev, I.; Patil, S.S.; Petrov, I.; Cappello, J.; Adelfinger, M.; Szalay, A.A. Oncolytic Virotherapy of Canine and Feline Cancer. Viruses 2014, 6, 2122-2137.

AMA Style

Gentschev I, Patil SS, Petrov I, Cappello J, Adelfinger M, Szalay AA. Oncolytic Virotherapy of Canine and Feline Cancer. Viruses. 2014; 6(5):2122-2137.

Chicago/Turabian Style

Gentschev, Ivaylo; Patil, Sandeep S.; Petrov, Ivan; Cappello, Joseph; Adelfinger, Marion; Szalay, Aladar A. 2014. "Oncolytic Virotherapy of Canine and Feline Cancer." Viruses 6, no. 5: 2122-2137.


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