Viruses 2014, 6(3), 1015-1036; doi:10.3390/v6031015
Review

B Cell Response and Mechanisms of Antibody Protection to West Nile Virus

1,* email and 2email
Received: 17 December 2013; in revised form: 7 February 2014 / Accepted: 8 February 2014 / Published: 3 March 2014
(This article belongs to the Special Issue West Nile Virus)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: West Nile virus (WNV) has become the principal cause of viral encephalitis in North America since its introduction in New York in 1999. This emerging virus is transmitted to humans via the bite of an infected mosquito. While there have been several candidates in clinical trials, there are no approved vaccines or WNV-specific therapies for the treatment of WNV disease in humans. From studies with small animal models and convalescent human patients, a great deal has been learned concerning the immune response to infection with WNV. Here, we provide an overview of a subset of that information regarding the humoral and antibody response generated during WNV infection.
Keywords: West Nile virus; flavivirus; humoral immunity; neutralizing antibody; epitopes; therapeutics
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MDPI and ACS Style

Austin, S.K.; Dowd, K.A. B Cell Response and Mechanisms of Antibody Protection to West Nile Virus. Viruses 2014, 6, 1015-1036.

AMA Style

Austin SK, Dowd KA. B Cell Response and Mechanisms of Antibody Protection to West Nile Virus. Viruses. 2014; 6(3):1015-1036.

Chicago/Turabian Style

Austin, S. K.; Dowd, Kimberly A. 2014. "B Cell Response and Mechanisms of Antibody Protection to West Nile Virus." Viruses 6, no. 3: 1015-1036.


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