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Viruses 2013, 5(11), 2690-2703; doi:10.3390/v5112690
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Roles of microRNAs in the Hepatitis B Virus Infection and Related Diseases

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Received: 22 September 2013 / Revised: 28 October 2013 / Accepted: 29 October 2013 / Published: 7 November 2013
(This article belongs to the Special Issue Viruses and miRNAs)
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Abstract

The hepatitis B virus (HBV) is a small enveloped DNA virus that belongs to the Hepadnaviridae family. HBV can cause acute and persistent infection which can lead to hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) play a crucial role in the main cellular events. The dysregulation of their expression has been linked to the development of the cancer as well as to viral interference. This chapter will describe the involvement of miRNAs in the case of HBV infection and their implication in the development of the HBV-related diseases.
Keywords: hepatitis B virus; microRNA; hepatocellular carcinoma hepatitis B virus; microRNA; hepatocellular carcinoma
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Thirion, M.; Ochiya, T. Roles of microRNAs in the Hepatitis B Virus Infection and Related Diseases. Viruses 2013, 5, 2690-2703.

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