Next Article in Journal
Ribavirin Protects Syrian Hamsters against Lethal Hantavirus Pulmonary Syndrome — After Intranasal Exposure to Andes Virus
Next Article in Special Issue
Role of Virus-Encoded microRNAs in Avian Viral Diseases
Previous Article in Journal
Detection of Coronaviruses in Bats of Various Species in Italy
Previous Article in Special Issue
Involvement of Eukaryotic Small RNA Pathways in Host Defense and Viral Pathogenesis
Viruses 2013, 5(11), 2690-2703; doi:10.3390/v5112690

Roles of microRNAs in the Hepatitis B Virus Infection and Related Diseases

Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
* Author to whom correspondence should be addressed.
Received: 22 September 2013 / Revised: 28 October 2013 / Accepted: 29 October 2013 / Published: 7 November 2013
(This article belongs to the Special Issue Viruses and miRNAs)
View Full-Text   |   Download PDF [920 KB, 12 May 2015; original version 12 May 2015]   |  


The hepatitis B virus (HBV) is a small enveloped DNA virus that belongs to the Hepadnaviridae family. HBV can cause acute and persistent infection which can lead to hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) play a crucial role in the main cellular events. The dysregulation of their expression has been linked to the development of the cancer as well as to viral interference. This chapter will describe the involvement of miRNAs in the case of HBV infection and their implication in the development of the HBV-related diseases.
Keywords: hepatitis B virus; microRNA; hepatocellular carcinoma hepatitis B virus; microRNA; hepatocellular carcinoma
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
MDPI and ACS Style

Thirion, M.; Ochiya, T. Roles of microRNAs in the Hepatitis B Virus Infection and Related Diseases. Viruses 2013, 5, 2690-2703.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


[Return to top]
Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert