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Viruses 2013, 5(10), 2573-2584; doi:10.3390/v5102573

CD8 and CD4 T Cells in West Nile Virus Immunity and Pathogenesis

1 Department of Immunology, University of Washington, Seattle, WA 98109, USA 2 The Howard Hughes Medical Institute, University of Washington, Seattle, WA 98109, USA
* Author to whom correspondence should be addressed.
Received: 2 September 2013 / Revised: 5 October 2013 / Accepted: 14 October 2013 / Published: 22 October 2013
(This article belongs to the Special Issue West Nile Virus)
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CD4 and CD8 T lymphocytes are adaptive immune cells that play a key role in the immune response to pathogens. They have been extensively studied in a variety of model systems and the mechanisms by which they function are well described. However, the responses by these cell types vary widely from pathogen to pathogen. In this review, we will discuss the role of CD8 and CD4 T cells in the immune response to West Nile virus infection.
Keywords: West Nile Virus; T cells; CD8 T cells; CD4 T cells West Nile Virus; T cells; CD8 T cells; CD4 T cells
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Netland, J.; Bevan, M.J. CD8 and CD4 T Cells in West Nile Virus Immunity and Pathogenesis. Viruses 2013, 5, 2573-2584.

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