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CD8 and CD4 T Cells in West Nile Virus Immunity and Pathogenesis
Department of Immunology, University of Washington, Seattle, WA 98109, USA
The Howard Hughes Medical Institute, University of Washington, Seattle, WA 98109, USA
* Author to whom correspondence should be addressed.
Received: 2 September 2013; in revised form: 5 October 2013 / Accepted: 14 October 2013 / Published: 22 October 2013
Abstract: CD4 and CD8 T lymphocytes are adaptive immune cells that play a key role in the immune response to pathogens. They have been extensively studied in a variety of model systems and the mechanisms by which they function are well described. However, the responses by these cell types vary widely from pathogen to pathogen. In this review, we will discuss the role of CD8 and CD4 T cells in the immune response to West Nile virus infection.
Keywords: West Nile Virus; T cells; CD8 T cells; CD4 T cells
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MDPI and ACS Style
Netland, J.; Bevan, M.J. CD8 and CD4 T Cells in West Nile Virus Immunity and Pathogenesis. Viruses 2013, 5, 2573-2584.
Netland J, Bevan MJ. CD8 and CD4 T Cells in West Nile Virus Immunity and Pathogenesis. Viruses. 2013; 5(10):2573-2584.
Netland, Jason; Bevan, Michael J. 2013. "CD8 and CD4 T Cells in West Nile Virus Immunity and Pathogenesis." Viruses 5, no. 10: 2573-2584.