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Recent Progress in Studies of Arterivirus- and Coronavirus-Host Interactions
School of Biological Sciences, Nanyang Technological Sciences, 60 Nanyang Drive, Singapore 637551, Singapore
* Author to whom correspondence should be addressed.
Received: 7 May 2012; in revised form: 30 May 2012 / Accepted: 14 June 2012 / Published: 19 June 2012
Abstract: Animal coronaviruses, such as infectious bronchitis virus (IBV), and arteriviruses, such as porcine reproductive and respiratory syndrome virus (PRRSV), are able to manifest highly contagious infections in their specific native hosts, thereby arising in critical economic damage to animal industries. This review discusses recent progress in studies of virus-host interactions during animal and human coronavirus and arterivirus infections, with emphasis on IBV-host cell interactions. These interactions may be directly involved in viral replication or lead to the alteration of certain signaling pathways, such as cell stress response and innate immunity, to facilitate viral replication and pathogenesis.
Keywords: virus-host interactions; coronavirus; arterivirus
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Cite This Article
MDPI and ACS Style
Zhong, Y.; Tan, Y.W.; Liu, D.X. Recent Progress in Studies of Arterivirus- and Coronavirus-Host Interactions. Viruses 2012, 4, 980-1010.
Zhong Y, Tan YW, Liu DX. Recent Progress in Studies of Arterivirus- and Coronavirus-Host Interactions. Viruses. 2012; 4(6):980-1010.
Zhong, Yanxin; Tan, Yong Wah; Liu, Ding Xiang. 2012. "Recent Progress in Studies of Arterivirus- and Coronavirus-Host Interactions." Viruses 4, no. 6: 980-1010.