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Viruses 2012, 4(3), 383-396; doi:10.3390/v4030383

Feline Immunodeficiency Virus in South America

1,* , 2
Received: 13 February 2012 / Revised: 22 February 2012 / Accepted: 24 February 2012 / Published: 14 March 2012
(This article belongs to the Special Issue Feline Retroviruses)
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The rapid emergence of AIDS in humans during the period between 1980 and 2000 has led to extensive efforts to understand more fully similar etiologic agents of chronic and progressive acquired immunodeficiency disease in several mammalian species. Lentiviruses that have gene sequence homology with human immunodeficiency virus (HIV) have been found in different species (including sheep, goats, horses, cattle, cats, and several Old World monkey species). Lentiviruses, comprising a genus of the Retroviridae family, cause persistent infection that can lead to varying degrees of morbidity and mortality depending on the virus and the host species involved. Feline immunodeficiency virus (FIV) causes an immune system disease in domestic cats (Felis catus) involving depletion of the CD4+ population of T lymphocytes, increased susceptibility to opportunistic infections, and sometimes death. Viruses related to domestic cat FIV occur also in a variety of nondomestic felids. This is a brief overview of the current state of knowledge of this large and ancient group of viruses (FIVs) in South America.
Keywords: feline immunodeficiency virus; South America; nondomestic felids; domestic cats feline immunodeficiency virus; South America; nondomestic felids; domestic cats
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Teixeira, B.M.; Hagiwara, M.K.; Cruz, J.C.M.; Hosie, M.J. Feline Immunodeficiency Virus in South America. Viruses 2012, 4, 383-396.

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