Clinical Characteristics and Genetic Variability of Human Rhinovirus in Mexico
AbstractHuman rhinovirus (HRV) is a leading cause of acute respiratory infection (ARI) in young children and infants worldwide and has a high impact on morbidity and mortality in this population. Initially, HRV was classified into two species: HRV-A and HRV-B. Recently, a species called HRV-C and possibly another species, HRV-D, were identified. In Mexico, there is little information about the role of HRV as a cause of ARI, and the presence and importance of species such as HRV-C are not known. The aim of this study was to determine the clinical characteristics and genetic variability of HRV in Mexican children. Genetic characterization was carried out by phylogenetic analysis of the 5′-nontranslated region (5′-NTR) of the HRV genome. The results show that the newly identified HRV-C is circulating in Mexican children more frequently than HRV-B but not as frequently as HRV-A, which was the most frequent species. Most of the cases of the three species of HRV were in children under 2 years of age, and all species were associated with very mild and moderate ARI. View Full-Text
- Supplementary File 1:
PDF-Document (PDF, 68 KB)
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Landa-Cardeña, A.; Morales-Romero, J.; García-Roman, R.; Cobián-Güemes, A.G.; Méndez, E.; Ortiz-Leon, C.; Pitalúa-Cortés, F.; Mora, S.I.; Montero, H. Clinical Characteristics and Genetic Variability of Human Rhinovirus in Mexico. Viruses 2012, 4, 200-210.
Landa-Cardeña A, Morales-Romero J, García-Roman R, Cobián-Güemes AG, Méndez E, Ortiz-Leon C, Pitalúa-Cortés F, Mora SI, Montero H. Clinical Characteristics and Genetic Variability of Human Rhinovirus in Mexico. Viruses. 2012; 4(2):200-210.Chicago/Turabian Style
Landa-Cardeña, Adriana; Morales-Romero, Jaime; García-Roman, Rebeca; Cobián-Güemes, Ana Georgina; Méndez, Ernesto; Ortiz-Leon, Cristina; Pitalúa-Cortés, Felipe; Mora, Silvia Ivonne; Montero, Hilda. 2012. "Clinical Characteristics and Genetic Variability of Human Rhinovirus in Mexico." Viruses 4, no. 2: 200-210.