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Converging Strategies in Expression of Human Complex Retroviruses
AbstractThe discovery of human retroviruses in the early 1980s revealed the existence of viral-encoded non-structural genes that were not evident in previously described animal retroviruses. Based on the absence or presence of these additional genes retroviruses were classified as ‘simple’ and ‘complex’, respectively. Expression of most of these extra genes is achieved through the generation of alternatively spliced mRNAs. The present review summarizes the genetic organization and expression strategies of human complex retroviruses and highlights the converging mechanisms controlling their life cycles.
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Cavallari, I.; Rende, F.; D'Agostino, D.M.; Ciminale, V. Converging Strategies in Expression of Human Complex Retroviruses. Viruses 2011, 3, 1395-1414.View more citation formats
Cavallari I, Rende F, D'Agostino DM, Ciminale V. Converging Strategies in Expression of Human Complex Retroviruses. Viruses. 2011; 3(8):1395-1414.Chicago/Turabian Style
Cavallari, Ilaria; Rende, Francesca; D'Agostino, Donna M.; Ciminale, Vincenzo. 2011. "Converging Strategies in Expression of Human Complex Retroviruses." Viruses 3, no. 8: 1395-1414.
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