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West Nile Virus: Immunity and Pathogenesis
Viruses 2011, 3(7), 982-1000; doi:10.3390/v3070982
Review

Correlates of Immunity to Filovirus Infection

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Received: 14 April 2011 / Revised: 14 June 2011 / Accepted: 16 June 2011 / Published: 27 June 2011
(This article belongs to the Special Issue Pathogenesis of Emerging and Re-Emerging RNA Viruses)
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Abstract

Filoviruses can cause severe, often fatal hemorrhagic fever in humans. Recent advances in vaccine and therapeutic drug development have provided encouraging data concerning treatment of these infections. However, relatively little is known about immune responses in fatal versus non-fatal filovirus infection. This review summarizes the published literature on correlates of immunity to filovirus infection, and highlights deficiencies in our knowledge on this topic. It is likely that there are several types of successful immune responses, depending on the type of filovirus, and the presence and timing of vaccination or drug treatment.
Keywords: filovirus; ebola; marburg; immunity
filovirus; ebola; marburg; immunity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Bradfute, S.B.; Bavari, S. Correlates of Immunity to Filovirus Infection. Viruses 2011, 3, 982-1000.

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