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Viruses 2011, 3(3), 204-216; doi:10.3390/v3030204
Commentary

A Strong Case for Viral Genetic Factors in HIV Virulence

1,* , 2
 and 3
1 Institute of Biology, Eötvös Loránd University, Pázmány P. s. 1/C, 1117 Budapest, Hungary 2 Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London W2 1PG, UK 3 Department of Microbiology, University of Washington School of Medicine, Seattle, WA 98195, USA
* Author to whom correspondence should be addressed.
Received: 19 January 2011 / Revised: 28 February 2011 / Accepted: 28 February 2011 / Published: 8 March 2011
(This article belongs to the Section Editorial)
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Abstract

HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four studies [1–4] published within a year has filled this important gap and has demonstrated a robust effect of the viral genotype on HIV virulence.
Keywords: HIV virulence; heritability; viral factors HIV virulence; heritability; viral factors
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Müller, V.; Fraser, C.; Herbeck, J.T. A Strong Case for Viral Genetic Factors in HIV Virulence. Viruses 2011, 3, 204-216.

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