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A Strong Case for Viral Genetic Factors in HIV Virulence
Institute of Biology, Eötvös Loránd University, Pázmány P. s. 1/C, 1117 Budapest, Hungary
Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London W2 1PG, UK
Department of Microbiology, University of Washington School of Medicine, Seattle, WA 98195, USA
* Author to whom correspondence should be addressed.
Received: 19 January 2011; in revised form: 28 February 2011 / Accepted: 28 February 2011 / Published: 8 March 2011
(This article belongs to the Section Editorial
Abstract: HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four studies [1–4] published within a year has filled this important gap and has demonstrated a robust effect of the viral genotype on HIV virulence.
Keywords: HIV virulence; heritability; viral factors
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Müller, V.; Fraser, C.; Herbeck, J.T. A Strong Case for Viral Genetic Factors in HIV Virulence. Viruses 2011, 3, 204-216.
Müller V, Fraser C, Herbeck JT. A Strong Case for Viral Genetic Factors in HIV Virulence. Viruses. 2011; 3(3):204-216.
Müller, Viktor; Fraser, Christophe; Herbeck, Joshua T. 2011. "A Strong Case for Viral Genetic Factors in HIV Virulence." Viruses 3, no. 3: 204-216.