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Viruses 2011, 3(3), 204-216; doi:10.3390/v3030204
Commentary

A Strong Case for Viral Genetic Factors in HIV Virulence

1,* , 2
 and
3
1 Institute of Biology, Eötvös Loránd University, Pázmány P. s. 1/C, 1117 Budapest, Hungary 2 Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London W2 1PG, UK 3 Department of Microbiology, University of Washington School of Medicine, Seattle, WA 98195, USA
* Author to whom correspondence should be addressed.
Received: 19 January 2011 / Revised: 28 February 2011 / Accepted: 28 February 2011 / Published: 8 March 2011
(This article belongs to the Section Editorial)
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Abstract

HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four studies [1–4] published within a year has filled this important gap and has demonstrated a robust effect of the viral genotype on HIV virulence.
Keywords: HIV virulence; heritability; viral factors HIV virulence; heritability; viral factors
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Müller, V.; Fraser, C.; Herbeck, J.T. A Strong Case for Viral Genetic Factors in HIV Virulence. Viruses 2011, 3, 204-216.

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