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Viruses 2010, 2(8), 1571-1576; doi:10.3390/v2081571
Commentary

Multitasking: Making the Most out of the Retroviral Envelope

1
 and
2,*
1 Department of Veterinary Medicine, University of Cambridge, Madingley Road, CB3 0ES, Cambridge, England, UK 2 Medical Research Council - University of Glasgow Centre for Virus Research, Institute for Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Scotland, UK
* Author to whom correspondence should be addressed.
Received: 16 June 2010 / Revised: 26 July 2010 / Accepted: 26 July 2010 / Published: 2 August 2010
(This article belongs to the Section Editorial)
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Abstract

Evasion of the host’s immune system is a required step for the establishment of viral infection. In this article, we discuss the recent findings of Heidmann and colleagues demonstrating that some retroviruses possess an immune suppressive (IS) domain "encrypted" within their envelope glycoprotein that is required to establish a successful infection in immunocompetent hosts [1].
Keywords: retroviruses; immune suppression; envelope retroviruses; immune suppression; envelope
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Varela, M.; Palmarini, M. Multitasking: Making the Most out of the Retroviral Envelope. Viruses 2010, 2, 1571-1576.

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