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Multitasking: Making the Most out of the Retroviral Envelope
Department of Veterinary Medicine, University of Cambridge, Madingley Road, CB3 0ES, Cambridge, England, UK
Medical Research Council - University of Glasgow Centre for Virus Research, Institute for Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Scotland, UK
* Author to whom correspondence should be addressed.
Received: 16 June 2010; in revised form: 26 July 2010 / Accepted: 26 July 2010 / Published: 2 August 2010
(This article belongs to the Section Editorial
Abstract: Evasion of the host’s immune system is a required step for the establishment of viral infection. In this article, we discuss the recent findings of Heidmann and colleagues demonstrating that some retroviruses possess an immune suppressive (IS) domain "encrypted" within their envelope glycoprotein that is required to establish a successful infection in immunocompetent hosts .
Keywords: retroviruses; immune suppression; envelope
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Varela, M.; Palmarini, M. Multitasking: Making the Most out of the Retroviral Envelope. Viruses 2010, 2, 1571-1576.
Varela M, Palmarini M. Multitasking: Making the Most out of the Retroviral Envelope. Viruses. 2010; 2(8):1571-1576.
Varela, Mariana; Palmarini, Massimo. 2010. "Multitasking: Making the Most out of the Retroviral Envelope." Viruses 2, no. 8: 1571-1576.